Article

Multi-Modal Profiling of Human Fetal Liver-Derived Hematopoietic Stem Cells Reveals the Molecular Signature of Engraftment Potential

2020-11-12

Abstract excerpt

<h4>SUMMARY</h4> The human hematopoietic stem cell (HSC) harbors remarkable regenerative potential that can be harnessed therapeutically. During early development, HSCs in the fetal liver (FL) undergo active expansion while simultaneously retaining robust engraftment capacity, yet the underlying molecular program responsible for their efficient engraftment remains unclear. We profiled 26,407 FL cells at both tran...

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Literature Corpus work: 95f7f4ae-c6b1-5100-be40-4fad00ca77eb
DOI: 10.1101/2020.11.11.378620

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