Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson's disease

18 Jul 2020

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disorder, for which no disease-modifying therapies are available to date. Although understanding of the precise aetiology of PD is incomplete, it is clear that age, genetic predisposition and environmental stressors increase the risk. At the cellular level, oxidative stress, chronic neuroinflammation, mitochondrial dysfunction and aberrant protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Genomics, phytochemicals, and oxidative stress
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32681666
DOI: 10.1002/med.21714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson's diseasePMID 32681666Read ↗

The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's DiseaseSemantic proximity Read ↗

Role of the Transcription Factor Nrf2 in Parkinson’s Disease: New InsightsSemantic proximity Read ↗

Activation of Nrf2 Neuroprotective Pathways for Treatment of Parkinson’s Disease: A State of Art ReviewSemantic proximity Read ↗

Targeting the Interplay Between Autophagy and the Nrf2 Pathway in Parkinson’s Disease with Potential Therapeutic ImplicationsSemantic proximity Read ↗

Nrf2: a modulator of Parkinson’s disease?Semantic proximity Read ↗

Normal and Pathological NRF2 Signalling in the Central Nervous SystemSemantic proximity Read ↗

α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant responseSemantic proximity Read ↗

Antioxidant and Anti-Inflammatory Defenses in Huntington’s Disease: Roles of NRF2 and PGC-1α, and Therapeutic StrategiesSemantic proximity Read ↗

Antioxidant and Anti-Inflammatory Defense in Huntington’s Disease: Role of NRF2 and Pgc-1α and Therapeutic StrategiesSemantic proximity Read ↗

The Nrf2-ARE Pathway: A Valuable Therapeutic Target for the Treatment of Neurodegenerative DiseasesSemantic proximity Read ↗

Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions.Semantic proximity Read ↗

Parkinson Disease Signaling Pathways, Molecular Mechanisms, and Potential Therapeutic Strategies: A Comprehensive ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.