Article

Atorvastatin Alleviates Behavioral Symptoms in MPTP-lesioned Mice: Associated With NOX2-mediated Autophagy and Oxidative Stress

2020-09-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons. It is characterized by static tremors, stiffness, slow movements, and gait disturbances, but it is also accompanied by anxiety and depression. Our previous study showed that statins, especially atorvastatin, could reduce the risk of PD, but the mechanism is still u...

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Literature Corpus work: 527e8175-604b-5eed-8859-83ee2dae2630
DOI: 10.21203/rs.3.rs-76724/v1

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