Article

SARS-CoV-2 Evolution in an HIV-Endemic Setting: A Genomic Epidemiology Study from Botswana

2025-11-22

Abstract excerpt

<h4>Background</h4> HIV infection can affect SARS-CoV-2 infection dynamics through prolonged viral replication and altered immune responses, but population-level genomic evidence from HIV-endemic settings is limited. Botswana, a country with high HIV prevalence and an established genomic surveillance infrastructure, provides an important setting to examine how host immune variation influences viral evolution duri...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 935056a2-7f94-50af-b4bf-c51892b5f79c
DOI: 10.1101/2025.11.21.25340589

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 Evolution in an HIV-Endemic Setting: A Genomic Epidemiology Study from BotswanaDOI 10.1101/2025.11.21.25340589Read

Phylodynamic Structure in the Botswana HIV EpidemicSemantic proximity Read

HIV status is not associated with SARS-CoV-2 viral load and longer duration of infection among people with well-controlled HIV and high COVID-19 vaccine coverageSemantic proximity Read

Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages Across Villages in Botswana Treatment-as-Prevention Trial.Semantic proximity Read

Phylodynamic analysis reveals disparate transmission dynamics of<i>Mycobacterium tuberculosis</i>-complex lineages in BotswanaSemantic proximity Read

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunitySemantic proximity Read

Global and regional molecular epidemiology of HIV-1 during 1990-2024: systematic review, global survey, and analysis of prevalence.Semantic proximity Read

Next generation sequencing of near-full length genome of norovirus GII.4 from Botswana.Semantic proximity Read

Genomic Evolution and Clade-Specific Mutation Signatures of Monkeypox Virus (Mpox) from 2022 to 2024 Reveal Distinct African Lineage DivergenceSemantic proximity Read

Human Immunodeficiency Virus (HIV) Genetic Diversity Informs Stage of HIV-1 Infection Among Patients Receiving Antiretroviral Therapy in Botswana.Semantic proximity Read

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escapeSemantic proximity Read

Intra-host SARS-CoV-2 diversity in immunocompromised people living with HIV provides insight into the evolutionary trajectory of SARS-CoV-2.Semantic proximity Read

Genomic and epidemiological surveillance of SARS-COV-2 variants during the pre-mass vaccination period in Botucatu, BrazilSemantic proximity Read