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Phylodynamic analysis reveals disparate transmission dynamics of<i>Mycobacterium tuberculosis</i>-complex lineages in Botswana

2024-11-02

Abstract excerpt

Tuberculosis epidemics have traditionally been conceptualized as arising from a single uniform pathogen. However, Mycobacterium tuberculosis -complex (Mtbc), the pathogen causing tuberculosis in humans, encompasses multiple lineages exhibiting genetic and phenotypic diversity that may be responsible for heterogeneity in TB transmission. We analysed a population-based dataset of 1,354 Mtbc whole-genome sequences co...

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Literature Corpus work
a0cb2357-f15e-5479-88fb-86765e9e5b6e
DOI
10.1101/2024.10.31.24316225
Open publication

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Phylodynamic analysis reveals disparate transmission dynamics of<i>Mycobacterium tuberculosis</i>-complex lineages in BotswanaDOI 10.1101/2024.10.31.24316225
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