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Article

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

13 Jan 2022

Abstract excerpt

Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties of the variants that come from these regions. We mapped neutralization of a SARS-CoV-2 strain that evolved over 6 months from ancestral virus in a person with advanced HIV disease in South Africa; this person was infected prior to emergence of the Beta and Delta variants. We longitudinally tracked the evolved virus and tested...

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PMID: 35120605
DOI: 10.1016/j.chom.2022.01.005

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