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RNA sequencing demonstrates <i>ex vivo</i> neocortical transcriptomic changes induced by epileptiform activity in male and female mice

2023-11-21

Abstract excerpt

Seizures are generally associated with epilepsy but may also be a symptom of many other neurological conditions. A hallmark of a seizure is the intensity of the local neuronal activation, which can drive large-scale gene transcription changes. Such changes in the transcriptional profile are likely to alter neuronal function, thereby contributing to the pathological process. Therefore, there is a strong clinical im...

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Literature Corpus work
932692c1-e67b-55db-a854-6cb57552192b
DOI
10.1101/2023.11.20.567411
Open publication

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RNA sequencing demonstrates <i>ex vivo</i> neocortical transcriptomic changes induced by epileptiform activity in male and female miceDOI 10.1101/2023.11.20.567411
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