Article

Transcriptomic profiles from stereo-EEGs reveal the local cell microenvironment in human epilepsy

2025-09-17

Abstract excerpt

<h4>Objectives: </h4> Our understanding of the pathomechanisms of epilepsy has improved through techniques that access the living human brain. We recently reported that explanted stereo-electroencephalography (SEEG) electrodes from patients with epilepsy carry residual biomolecules and cells which may be utilised for transcriptome and DNA methylation profiling. <h4>Methods:</h4> Here, we applied bioinformatic and...

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Literature Corpus work: 19083a81-47b8-5c09-9f41-f671fedbc98c
DOI: 10.1101/2025.09.16.676570

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