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Article

Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks.

Physiological genomics - 20 Aug 2007

Kedmi Merav, Orr-Urtreger Avi

Abstract excerpt

Nicotine, acting through the neuronal nicotinic acetylcholine receptors (nAChRs), can induce seizures in mice. We aimed to study brain transcriptional response to seizure and to identify genes whose expression is altered after nicotine-induced seizures. Whole brains of untreated mice were compared with brains 1 h after seizure activity, using Affymetrix U74Av2 microarrays. Experimental groups included wild-type...

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Identifiers

PMID: 17456735
DOI: 10.1152/physiolgenomics.00288.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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