Back to search

Article

Low grade inflammation in the epileptic hippocampus contrasts with explosive inflammation occurring in the acute phase following <i>status epilepticus</i> in rats: translation to patients with epilepsy

2021-03-26

Abstract excerpt

<h4>ABSTRACT</h4> There is still a lack of robust data, acquired identically and reliably from tissues either surgically resected from patients with mesial temporal lobe epilepsy (mTLE) or collected in animal models, to answer the question of whether the degree of inflammation of the hippocampus differs between mTLE patients, and between epilepsy and epileptogenesis. Here, using highly calibrated RTqPCR, we show...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
eac99907-7d97-5332-a31f-1a681a5b70a8
DOI
10.1101/2021.03.25.436701
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Low grade inflammation in the epileptic hippocampus contrasts with explosive inflammation occurring in the acute phase following <i>status epilepticus</i> in rats: translation to patients with epilepsyDOI 10.1101/2021.03.25.436701
RNA sequencing demonstrates <i>ex vivo</i> neocortical transcriptomic changes induced by epileptiform activity in male and female miceSemantic proximity
RNA Sequencing Demonstrates Ex Vivo Neocortical Transcriptomic Changes Induced by Epileptiform Activity in Male and Female MiceSemantic proximity
Transcriptome profiling implicates a role for Wnt signaling during epileptogenesis in a mouse model of temporal lobe epilepsySemantic proximity
Increased Immunoglobulin and Proteoglycan Synthesis in Resected Hippocampal Tissue Predicts Postsurgical Seizure Recurrence in Human Temporal Lobe EpilepsySemantic proximity
Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesisSemantic proximity
Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice.Semantic proximity
Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy.Semantic proximity
EPILEPTOGENESIS INHIBITS THE CIRCADIAN CLOCK AND RESHAPES THE DIURNAL TRANSCRIPTOMIC RHYTHMICITY IN THE MOUSE HIPPOCAMPUSSemantic proximity
High concordance between hippocampal transcriptome of the intraamygdala kainic acid model and human temporal lobe epilepsySemantic proximity
High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsySemantic proximity
Possible role of the innate immunity in temporal lobe epilepsySemantic proximity
Neuroinflammation: A Signature or a Cause of Epilepsy?Semantic proximity
Select a neighboring publication to make it the new centre.