Article

Subcellular Characterization of the Molecular Determinants of Ebola VP40 Trafficking and Assembly

2026-02-16

Abstract excerpt

Ebola virus is a single-stranded negative-sense RNA virus that can cause severe hemorrhagic fevers in humans. Ebola virus, along with other members of the filoviridae family, produce virions with a characteristic filamentous morphology. VP40, the filovirus matrix protein, is responsible for curving the host plasma membrane (PM). Expression of VP40 and the assembly of the matrix layer results in the budding of fila...

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Literature Corpus work: 93120f4d-8592-524c-989c-500c21c8805f
DOI: 10.64898/2026.02.13.705837

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