Article

Structural basis of Ebola virus nucleocapsid assembly and functions

2024-02-19

Abstract excerpt

The Ebola virus, a member of the Filoviridae family, causes severe hemorrhagic fever in humans. Filamentous virions contain a helical nucleocapsid responsible for genome transcription, replication, and packaging into progeny virions. The nucleocapsid consists of a helical nucleoprotein (NP)-viral genomic RNA complex forming the core structure, to which VP24 and VP35 bind externally. Two NPs, each paired with a VP2...

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Literature Corpus work: e5544158-e012-5ece-8efa-25858b2ba307
DOI: 10.1101/2024.02.19.580633

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