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Population Pharmacokinetics and Dose Optimization of Tacrolimus in Chinese Adult Patients with Myasthenia Gravis

2026-05-12

Abstract excerpt

<b>Introduction: </b>Tacrolimus is an effective immunosuppressive agent for myasthenia gravis, but exhibits a narrow therapeutic window and substantial interindividual variability in blood concentrations, complicating dose optimization. This study aimed to develop a population pharmacokinetic model of tacrolimus in Chinese adult patients with myasthenia gravis to optimize dosing regimens. <b>Methods: </b>This stud...

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Literature Corpus work
92fda08d-9408-589d-a7fb-5b6eb19373f3
DOI
10.22541/authorea.15003096/v1
Open publication

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Population Pharmacokinetics and Dose Optimization of Tacrolimus in Chinese Adult Patients with Myasthenia GravisDOI 10.22541/authorea.15003096/v1
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