Article

Tacrolimus Population Pharmacokinetic Model in Chinese Patients with Nephrotic Syndrome and Dosing Regimen Identification Using Monte Carlo Simulations

2024-01-31

Abstract excerpt

<h4>Aim: </h4> The study aimed to establish a population pharmacokinetic (PPK) model for Chinese patients with nephrotic syndrome using the patient genotype and Wuzhi capsule dose as the main test factors. <h4>Methods:</h4> Adult patients with nephrotic syndrome receiving tacrolimus treatment were enrolled. A nonlinear mixed effects model was used to determine the influencing factors of inter-individual tacrolimus...

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Literature Corpus work: 2548cd6e-baa7-5824-8c19-f30bc04d2079
DOI: 10.22541/au.170669901.15480911/v1

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