Article

Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers

2018-05-30

Abstract excerpt

<h4>ABSTRACT</h4> Epigenomic data on transcription factor occupancy and chromatin accessibility can elucidate the developmental origin of cancer cells and reveal the enhancer landscape of key oncogenic transcriptional regulators. However, in many cancers, epigenomic analyses have been limited, and computational methods to infer regulatory networks in tumors typically use expression data alone, or rely on transcri...

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Literature Corpus work: 02cc554b-fd6a-51c3-ac29-6f2cb28f1851
DOI: 10.1101/333757

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