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Article

High-throughput propagation of human prostate tissue from induced-pluripotent stem cells

2019-05-14

Abstract excerpt

Primary culture of human prostate organoids is slow, inefficient and laborious. To overcome this, we demonstrate a new high-throughput model where rapidly proliferating and easily handled induced pluripotent stem cells, for the first time, enable generation of human prostate tissue in vivo and in vitro. Using a co-culture technique with urogenital sinus mesenchyme, we recapitulated the in situ prostate histology,...

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Literature Corpus work
929d0a52-3cfd-5c2c-8426-7d50c5bc4368
DOI
10.1101/637876
Open publication

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