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Genomic and Prognostic Heterogeneity Among RAS/BRAFV600E/TP53 Co-Mutated Resectable Colorectal Liver Metastases

2020-08-07

Abstract excerpt

<h4>Background: </h4> Hepatic resection is potentially curative for patients with colorectal liver metastases, but the treatment benefit varies. KRAS / NRAS ( RAS) / TP53 co-mutations are associated with a poor prognosis after resection, but there is large variation in patient outcome within the mutation groups, and genetic testing is currently not used to determine the likely benefit from surgery. We have investi...

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Literature Corpus work
928beab7-5e1f-5153-81eb-58faf0a0375f
DOI
10.21203/rs.3.rs-54736/v1
Open publication

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Genomic and Prognostic Heterogeneity Among RAS/BRAFV600E/TP53 Co-Mutated Resectable Colorectal Liver MetastasesDOI 10.21203/rs.3.rs-54736/v1
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