Mutation Status of RAS, TP53 , and SMAD4 is Superior to Mutation Status of RAS Alone for Predicting Prognosis after Resection of Colorectal Liver Metastases

Abstract excerpt

Abstract Purpose: Somatic gene mutations have been increasingly recognized to impact prognosis following resection of colorectal liver metastases (CLM). We aimed to determine the impact of combinations of somatic mutations on survival in patients undergoing CLM resection. Experimental Design: We identified patients who underwent initial CLM resection during 2007–2017 and had genetic sequencing data available....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer Genomics and Diagnostics
• Share to Colorectal Cancer Treatments and Studies
• Share to Hepatocellular Carcinoma Treatment and Prognosis