Article

Emerging evidence for the Prominent correlation between the transcription of P4HB gene and pregnancy outcomes as well as embryonic development

2024-04-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Prolyl 4-hydroxylase beta polypeptide, encoded by the P4HB gene, belongs to the protein disulfide isomerases family, implicated in multiple risk factor biological processes related to the occurrence of adverse pregnancy outcomes and embryonic development. Changes in P4HB gene expression play an important role in pathophysiologic processes. Little is known about...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 92413876-d65e-5bbf-9e43-3205da29baf8
DOI: 10.21203/rs.3.rs-4225336/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Emerging evidence for the Prominent correlation between the transcription of P4HB gene and pregnancy outcomes as well as embryonic developmentDOI 10.21203/rs.3.rs-4225336/v1Read

Analysis of splice variants of the human protein disulfide isomerase (P4HB) gene.Semantic proximity Read

Post-Transcriptional Modification by Alternative Splicing and Pathogenic Splicing Variants in Cardiovascular Development and Congenital Heart DefectsSemantic proximity Read

Identification of globin switching-related genes and RNAs via transcriptomic profiling of nucleated red blood cells isolated from the cord blood of preterm and full-term newborns Semantic proximity Read

Snrnp25 is a candidate for the peri-implantation lethal phenotype of the Hba deletionsSemantic proximity Read

Debunking the “junk”: Unraveling the role of lncRNA–miRNA–mRNA networks in fetal hemoglobin regulationSemantic proximity Read

Bulk RNA-sequencing, single-cell RNA-sequencing analysis, and experimental validation reveal iron metabolism-related genes CISD2 and CYP17A1 are potential diagnostic markers for recurrent pregnancy lossSemantic proximity Read

Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome.Semantic proximity Read

Mapping Chemical-Gene Interactions for Developmental Lethality and Pregnancy LossSemantic proximity Read

Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review)Semantic proximity Read

Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle.Semantic proximity Read

HRH4 may be a new predictor for preterm birthSemantic proximity Read

Mammalian Pabpc4 is non-essential for development, but has roles in growth, post-natal survival and haematopoiesisSemantic proximity Read