Article

Mapping Chemical-Gene Interactions for Developmental Lethality and Pregnancy Loss

2025-10-07

Abstract excerpt

<h4>Summary</h4> Pregnancy loss affects 10–15% of clinically recognized pregnancies and arises from both genetic and environmental influences, yet evidence linking chemicals to pregnancy loss genes is rarely organized by gestational timing, maternal–fetal compartment, or lethality context. To address this gap, we integrated lethality-associated gene annotations from Intolerome with chemical–gene interactions from...

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Literature Corpus work: b0ce33c1-9530-5b31-a787-ac31e0fb40ec
DOI: 10.1101/2025.10.03.25337209

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