Article

Snrnp25 is a candidate for the peri-implantation lethal phenotype of the Hba deletions

2025-04-22

Abstract excerpt

<title>Abstract</title> <p>Mutations in adult hemoglobin alpha genes in humans lead to blood disorders commonly known as α-thalassemia. In search of a mouse model for this disease, mutagenesis screens have identified several deletions that resemble these phenotypes. The <italic>Hba</italic><sup><italic>b2(th)</italic></sup> deletion, in particular, replicates the characteristics of alpha-thalassemia minor in hete...

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Literature Corpus work: 8673e758-a0d3-5a76-8412-00a2e03bc63c
DOI: 10.21203/rs.3.rs-6335781/v1

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