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Genome-wide CRISPR Screening Identifies the Pivotal Role of ANKRD42 in Colorectal Cancer Metastasis Through EMT Regulation

2024-02-20

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC), a pervasive and lethal malignancy of the gastrointestinal cancer, imposes significant challenges due to the occurrence of distant metastasis in advanced stages. Understanding the intricate regulatory mechanisms driving CRC distant metastasis is of paramount importance. <h4>Methods: </h4>: To faithfully recapitulate CRC liver metastasis, we innovatively employed in vi...

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Literature Corpus work
923e1403-5e54-555b-9fd8-5e2c08bfb224
DOI
10.21203/rs.3.rs-3960416/v1
Open publication

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Genome-wide CRISPR Screening Identifies the Pivotal Role of ANKRD42 in Colorectal Cancer Metastasis Through EMT RegulationDOI 10.21203/rs.3.rs-3960416/v1
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