Back to search

Article

Primary oocytes with cellular senescence features are involved in ovarian aging in mice

2024-01-09

Abstract excerpt

In mammalian females, quiescent primordial follicles serve as the ovarian reserve and sustain normal ovarian function and egg production via folliculogenesis. The loss of primordial follicles causes ovarian aging. Cellular senescence, characterized by cell cycle arrest and production of the senescence-associated secretory phenotype (SASP), is associated with tissue aging. In the present study, we report that some...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
922d6970-e0a4-53dd-bc32-2464413e5ef0
DOI
10.1101/2024.01.08.574768
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Primary oocytes with cellular senescence features are involved in ovarian aging in miceDOI 10.1101/2024.01.08.574768
Primary oocytes with cellular senescence features are involved in ovarian aging in miceSemantic proximity
The role of cellular senescence in ovarian agingSemantic proximity
Nano-encapsulated senolytic cocktail attenuates germ cell senescence in female miceSemantic proximity
Aging of Oocyte, Ovary, and Human ReproductionSemantic proximity
Positive and negative effects of cellular senescence during female reproductive aging and pregnancySemantic proximity
Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypesSemantic proximity
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventionsSemantic proximity
Cell-Free Fat Extract Improves Ovarian Function and Fertility in Mice With Advanced AgeSemantic proximity
Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.Semantic proximity
Low estrogen level in aged mice leads to abnormal oogenesis affecting the quality of surrounded nucleolus-type immature oocytesSemantic proximity
Insufficiency of melatonin in follicular fluid is a reversible cause for advanced maternal age-related aneuploidy in oocytesSemantic proximity
The Role of Cellular Senescence in Cyclophosphamide-Induced Primary Ovarian InsufficiencySemantic proximity
Select a neighboring publication to make it the new centre.