Article
Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes
16 Oct 2023
Abstract excerpt
Female fertility is negatively correlated with age, with noticeable declines in oocyte quantity and quality until menopause. To understand this physiological process and evaluate human approaches for treating age-related infertility, preclinical studies in appropriate animal models are needed. Thus, we aimed to characterize an immunodeficient physiological aging mouse model displaying ovarian characteristics of...
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