Nano-encapsulated senolytic cocktail attenuates germ cell senescence in female mice

Abstract excerpt

Low-quality oocytes directly affect fertilization and embryonic development, contributing to infertility in women, while germ cell senescence leads to reduced germ cell numbers and decreased egg quality. Dasatinib and quercetin (D and Q), as senolytic drugs, have been extensively explored in different age-related diseases. However, their effects on in vitro cultured senescent oocytes and the molecular mechanisms...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Reproductive Health and Technologies
• Share to Sperm and Testicular Function