Article

Intra-peritoneal transplantation for efficient and easy generation of experimental acute myeloid leukemia in mice

2022-08-05

Abstract excerpt

<h4>Objective</h4> There is an unmet need for novel therapies to treat acute myeloid leukemia (AML) and the associated relapse that involves leukemia stem cells (LSCs). An experimental AML rodent model to test therapies based on successfully transplanting these cells via retro-orbital injections in recipient mice is fraught with challenges. The aim of this study was to develop an easy, reliable, and consistent me...

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Literature Corpus work: 922be5fa-3936-5677-9c97-b3c4f1c3f50c
DOI: 10.1101/2022.08.03.502696

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