Article
Murine models of human acute myeloid leukemia.
Cancer treatment and research - 1 Jan 2010
Fortier Julie M, Graubert Timothy A
Abstract excerpt
Primary human AML cells can be isolated and studied in vitro, but many experimental questions can only be addressed using in vivo models. In particular, tractable animal models are needed to test novel therapies. The genetic complexity of human AML poses significant challenges for the generation...
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