Article

High LETM1 Expression Associates with Impaired Mitophagy and Bad Prognosis in Diffuse Large B-cell Lymphomas and Acute Myeloid Leukemias

2024-07-29

Abstract excerpt

Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) is a mitochondrial inner membrane protein involved in mitochondrial morphology and homeostasis. LETM1 is highly expressed in many human solid cancers and correlates with poor prognosis possibly due to mitochondrial dysfunction. However, the functional role of LETM1 in the progression of hematological malignancies remains to be elucidated. In this st...

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Literature Corpus work: 91f9c4a5-f7e6-5ee3-a007-855ce7ac2e59
DOI: 10.20944/preprints202407.2292.v1

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