Article

Mitophagy-Driven Prognosis in Pediatric Acute Myeloid Leukemia: A New Frontier

2025-04-16

Abstract excerpt

<h4>Background: </h4> Mitophagy is a crucial mitochondrial quality control mechanism that removes dysfunctional mitochondria via lysosomal degradation, maintaining cellular homeostasis. Cancer cells exploit this process to sustain mitochondrial function, promote tumor renewal, and enhance therapy resistance. While mitophagy has been extensively studied in solid tumors, its role in Acute Myeloid Leukemia (AML), par...

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Literature Corpus work: 1d367ad4-9c89-5051-8390-9d40430763bc
DOI: 10.22541/au.174479256.66064592/v1

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