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Bayesian‐optimized deep learning for identifying essential genes of mitophagy and fostering therapies to combat drug resistance in human cancers

1 Jan 2025

Abstract excerpt

Dysregulated mitophagy is essential for mitochondrial quality control within human cancers. However, identifying hub genes regulating mitophagy and developing mitophagy-based treatments to combat drug resistance remains challenging. Herein, BayeDEM (Bayesian-optimized Deep learning for identifying Essential genes of Mitophagy) was proposed for such a task. After Bayesian optimization, BayeDEM demonstrated its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39834330
DOI: 10.1111/jcmm.18254

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