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Mitophagy in gynecological malignancies: roles, advances, and therapeutic potential

5 Dec 2024

Abstract excerpt

Mitophagy is a process in which impaired or dysfunctional mitochondria are selectively eliminated through the autophagy mechanism to maintain mitochondrial quality control and cellular homeostasis. Based on specific target signals, several mitophagy processes have been identified. Defects in mitophagy are associated with various pathological conditions, including neurodegenerative disorders, cardiovascular...

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PMID: 39639053
DOI: 10.1038/s41420-024-02259-x

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