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BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma

2 Sept 2023

Abstract excerpt

There is an urgent need for novel diagnostic and therapeutic strategies for patients with Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) is a member of the BCL2 family regulating cell growth and apoptosis in different types of tumors. However, the clinical significance, biological role, and potential mechanism in GBM remain unexplored. In this study, we showed that BCL2L13...

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PMID: 37660127
DOI: 10.1038/s41419-023-06112-4

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