Article

Genotypic and phenotypic consequences of domestication in dogs

2024-05-05

Abstract excerpt

Runs of homozygosity (ROH) are genomic regions that arise when two copies of identical haplotypes are inherited from a shared common ancestor. In this study, we leverage ROH to identify associations between genetic diversity and non-disease phenotypes in Canis lupus familiaris (dogs). We find significant association between the ROH inbreeding coefficient (F ROH ) and several phenotypic traits. These traits inclu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 91810a71-da26-5f23-b406-a5c38500bf0d
DOI: 10.1101/2024.05.01.592072

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genotypic and phenotypic consequences of domestication in dogsDOI 10.1101/2024.05.01.592072Read

Fine-scale resolution and analysis of runs of homozygosity in domestic dogsSemantic proximity Read

The impact of identity-by-descent on fitness and disease in natural and domesticated <i>Canid</i> populationsSemantic proximity Read

The impact of identity by descent on fitness and disease in dogs.Semantic proximity Read

A simple genetic architecture underlies morphological variation in dogs.Semantic proximity Read

Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and healthSemantic proximity Read

Genetic analysis of the modern Australian labradoodle dog breed reveals an excess of the poodle genome.Semantic proximity Read

Leading the way: canine models of genomics and disease.Semantic proximity Read

Rethinking dog domestication by integrating genetics, archeology, and biogeography.Semantic proximity Read

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication.Semantic proximity Read

Canine genomics and genetics: running with the pack.Semantic proximity Read

Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogsSemantic proximity Read

Evolutionary genomics of dog domestication.Semantic proximity Read