Article

Fine-scale resolution and analysis of runs of homozygosity in domestic dogs

2018-05-07

Abstract excerpt

<h4>Abstract/Summary</h4> Inbreeding and consanguinity leave distinct genomic traces, most notably long genomic tracts that are identical by descent and completely homozygous. These runs of homozygosity (ROH) can contribute to inbreeding depression if they contain deleterious variants that are fully or partially recessive. Several lines of evidence have been used to show that long (> 5 megabase (Mb)) ROH are disp...

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Literature Corpus work: 0fc868c5-e717-504c-ba5a-37c314af89b2
DOI: 10.1101/315770

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