Genotypic and phenotypic consequences of domestication in dogs.

doi:10.1093/g3journal/jkag195

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Article

Genotypic and phenotypic consequences of domestication in dogs.

G3 (Bethesda, Md.) - 2 Sept 2026

Sweetalana, Nataneli Shirin, Huang Shengmiao, Mooney Jazlyn A, Szpiech Zachary A

Abstract excerpt

Runs of homozygosity (ROH) are genomic regions that arise when identical haplotypes are inherited from a shared ancestor. In this study, we explored ROH across 556 whole-genome sequences from domesticated and non-domesticated dogs. Then, we leveraged ROH from 466 breed dogs, representing 13 breed groups and 13 phenotypic traits, to investigate associations between genetic diversity and non-disease phenotypes. We...

Read the complete abstract on PubMed

Topics

Animals
Dogs
Domestication
Phenotype
Homozygote
Genotype
Inbreeding

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Variation

Genome-Wide Association Study

Polymorphism, Single Nucleotide

Breeding

Haplotypes

Quantitative Trait Loci

Genetic Association Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42466647
DOI: 10.1093/g3journal/jkag195
PMCID: PMC13535439

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