Article
Measures of Homozygosity and Relationship to Genetic Diversity in the Bearded Collie Breed.
Genes - 27 Mar 2025
Belanger Janelle M, Gershony Liza C, Bell Jerold S, Hytönen Marjo K, Lohi Hannes, Lindblad-Toh Kerstin, Tengvall Katarina, Sell Elsa, Famula Thomas R, Oberbauer Anita M
Abstract excerpt
Background: Genetic diversity in closed populations, such as pedigree dogs, is of concern for maintaining the health and vitality of the population in the face of evolving challenges. Measures of genetic diversity rely upon estimates of homozygosity without consideration of whether the homozygosity is desirable or undesirable or if heterozygosity has a functional impact. Pedigree coefficients of inbreeding have...
Read the complete abstract on PubMedTopics
- Animals
- Homozygote
- Dogs
- Pedigree
- Polymorphism, Single Nucleotide
- Inbreeding