Article

Frequency of Ras Mutations (Kras, Nras, Hras) in Human Solid Cancer

2017-07-26

Abstract excerpt

RAS oncogene affects numerous cellular functions including growth, proliferation, apoptosis, migration, division and differentiation of the cells. It has 3 known isoforms as Harvey- RAS (HRAS), Kirsten - RAS (KRAS) and NeuroblastomaRAS (NRAS). RAS has an intrinsic GTPase activity. It encodes proteins binding the guanine nucleotides. KRAS and HRAS were discovered in studies carried out on viruses leading to cancer....

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Literature Corpus work: 915a4010-ab4c-5de4-9af1-a7fdaf64f88f
DOI: 10.14744/ejmo.2017.22931

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