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Article

Kirsten Ras* oncogene: significance of its discovery in human cancer research.

Oncotarget - 19 Jul 2016

Tsuchida Nobuo, Murugan Avaniyapuram Kannan, Grieco Michele

Abstract excerpt

The KRAS/ K-RAS oncogene is crucially involved in human cancer. The term "oncogene" -- i.e., a gene able to transform a normal cell into a tumor cell - was introduced in 1969, but the word was not used in the human carcinogenesis literature until much later. Transforming Kras and Hras oncogenes from the Kirsten and Harvey sarcoma viruses were not identified until the early 1980s due to the complicated structures...

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Source

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Identifiers

PMID: 27102293
DOI: 10.18632/oncotarget.8773
PMCID: PMC5216832

Genes

KRAS
EGFR
HRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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