Article
Genetic variation in chromosome Y regulates susceptibility to influenza A virus infection.
Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 2017
Krementsov Dimitry N, Case Laure K, Dienz Oliver, Raza Abbas, Fang Qian, Ather Jennifer L, Poynter Matthew E, Boyson Jonathan E, Bunn Janice Y, Teuscher Cory
Abstract excerpt
Males of many species, ranging from humans to insects, are more susceptible than females to parasitic, fungal, bacterial, and viral infections. One mechanism that has been proposed to account for this difference is the immunocompetence handicap model, which posits that the greater infectious disease burden in males is due to testosterone, which drives the development of secondary male sex characteristics at the...
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