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Article

Type 1 Diabetes and Multiple Sclerosis Share General Autoimmunity Genetic Variation.

Genes - 30 Apr 2026

Steri Maristella, Testori Alessandro, Orrù Valeria, Zoledziewska Magdalena

Abstract excerpt

Background/Objectives: Type 1 diabetes (T1D) and multiple sclerosis (MS) are autoimmune, multifactorial, organ-specific disorders mediated by immune cells. Their co-occurrence has been partially attributed to shared genetics and environmental factors. We aimed to dissect the shared genetic architecture between T1D and MS using large-scale genome-wide association studies (GWASs) and colocalization analyses....

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Topics

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Share to Autoimmunity
Share to Bayes Theorem
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Genome-Wide Association Study

Share to Multiple Sclerosis

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 42194988
DOI: 10.3390/genes17050531
PMCID: PMC13205159

Genes

DLL1
EOMES
LAT
RGS14
SESN3
SLC25A47
UBAC2
WARS1
ZEB1
ZNF438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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