Article

Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator

2023-12-28

Abstract excerpt

Susceptibility of human cells to cold stress restricts the use of therapeutic hypothermia and long-term preservation of organs at low temperatures. In contrast, cells of mammalian hibernators possess remarkable cold resistance, but little is known about the molecular mechanisms underlying this phenomenon. In this study, we conducted a gain-of-function screening of genes that confer cold resistance to cold-vulnerab...

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Literature Corpus work: 1f545b01-0983-5c20-9fdb-ae377b25ea4a
DOI: 10.1101/2023.12.27.573489

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