Article

Mutational spectrum of breast cancer by shallow whole-genome sequencing of cfDNA and tumor gene panel analysis

2023-06-15

Abstract excerpt

Breast cancer (BC) has various molecular subgroups with differing risks and treatments. Tumor biopsies for BC detection are invasive and may not reflect tumor heterogeneity. Liquid biopsies have become relevant because they might overcome these limitations. We evaluated the feasibility to detect somatic copy number alterations (SCNAs) in BC using shallow whole genome sequencing (sWGS) in cfDNA from archived sample...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 909760ca-d76a-5601-b653-b0625c762ce2
DOI: 10.21203/rs.3.rs-3015629/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mutational spectrum of breast cancer by shallow whole-genome sequencing of cfDNA and tumor gene panel analysisDOI 10.21203/rs.3.rs-3015629/v1Read

Mutational spectrum of breast cancer by shallow whole-genome sequencing of cfDNA and tumor gene panel analysis.Semantic proximity Read

Genetic profiles of cervical tumors by high-throughput sequencing for personalized medical care.Semantic proximity Read

Exomes of Ductal Luminal Breast Cancer Patients from Southwest Colombia: Gene Mutational Profile and Related Expression Alterations.Semantic proximity Read

Identification of somatic mutational landscape across Indian breast cancer cases by whole exome sequencing.Semantic proximity Read

Somatic mutational landscape across Indian breast cancer cases by whole exome sequencing.Semantic proximity Read

Technical Validation of a Next-Generation Sequencing Assay for Detecting Clinically Relevant Levels of Breast Cancer-Related Single-Nucleotide Variants and Copy Number Variants Using Simulated Cell-Free DNA.Semantic proximity Read

Pathway Mutations in Breast Cancer Using Whole-Exome SequencingSemantic proximity Read

Accuracy of analysis of cfDNA for detection of single nucleotide variants and copy number variants in breast cancerSemantic proximity Read

Insight into the heterogeneity of breast cancer through next-generation sequencing.Semantic proximity Read

The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers.Semantic proximity Read

Multimodal analysis of cell-free DNA enhances differentiation of early-stage breast cancer from benign lesions and healthy individualsSemantic proximity Read

Targeted mutation detection in breast cancer using MammaSeq™Semantic proximity Read