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Exomes of Ductal Luminal Breast Cancer Patients from Southwest Colombia: Gene Mutational Profile and Related Expression Alterations.

Biomolecules - 30 Apr 2020

Cortes-Urrea Carolina, Bueno-Gutiérrez Fernando, Solarte Melissa, Guevara-Burbano Miguel, Tobar-Tosse Fabian, Vélez-Varela Patricia E, Bonilla Juan Carlos, Barreto Guillermo, Velasco-Medina Jaime, Moreno Pedro A, Rivas Javier De Las

Abstract excerpt

Cancer is one of the leading causes of mortality worldwide. Breast cancer is the most frequent cancer in women, and in recent years it has become a serious public health problem in Colombia. The development of large-scale omic techniques allows simultaneous analysis of all active genes in tumor cells versus normal cells, providing new ways to discover the drivers of malignant transformations. Whole exome...

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PMID: 32365829
DOI: 10.3390/biom10050698
PMCID: PMC7277822

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