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Somatic mutational landscape across Indian breast cancer cases by whole exome sequencing.

Scientific reports - 12 Aug 2024

Kumar Rahul, Awasthi Supriya, Pradhan Dibyabhaba, Kumar Rakesh, Goel Harsh, Singh Jay, Haider Imran, Deo S V S, Kumar Chitresh, Srivastava Anurag, Bhatnagar Amar, Kumar Rakesh, Lakshmi S, Augustine Paul, Ranjan Amar, Chopra Anita, Gogia Ajay, Batra Atul, Mathur Sandeep, Rath Goura Kishor, Kaur Tanvir, Dhaliwal R S, Mathew Aleyamma, Agrawal Usha, Hussain Showket, Tanwar Pranay

Abstract excerpt

Breast cancer (BC) has emerged as the most common malignancy among females. The genomic profile of BC is diverse in nature and complex due to heterogeneity among various geographically different ethnic groups. The primary objective of this study was to carry out a comprehensive mutational analysis of Indian BC cases by performing whole exome sequencing. The cohort included patients with a median age of 48 years....

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Biomarkers, Tumor
Breast Neoplasms
DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Exome Sequencing

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PMID: 39134585
DOI: 10.1038/s41598-024-65148-4
PMCID: PMC11319672

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