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Article

Genetic profiles of cervical tumors by high-throughput sequencing for personalized medical care.

Cancer medicine - 1 Oct 2015

Muller Etienne, Brault Baptiste, Holmes Allyson, Legros Angelina, Jeannot Emmanuelle, Campitelli Maura, Rousselin Antoine, Goardon Nicolas, Frébourg Thierry, Krieger Sophie, Crouet Hubert, Nicolas Alain, Sastre Xavier, Vaur Dominique, Castéra Laurent

Abstract excerpt

Cancer treatment is facing major evolution since the advent of targeted therapies. Building genetic profiles could predict sensitivity or resistance to these therapies and highlight disease-specific abnormalities, supporting personalized patient care. In the context of biomedical research and clinical diagnosis, our laboratory has developed an oncogenic panel comprised of 226 genes and a dedicated bioinformatic...

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Anaplastic Lymphoma Kinase
F-Box Proteins
F-Box-WD Repeat-Containing Protein 7
Genes, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precision Medicine

Receptor Protein-Tyrosine Kinases

Ubiquitin-Protein Ligases

Uterine Cervical Neoplasms

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Open in PubMed Open full text

Identifiers

PMID: 26155992
DOI: 10.1002/cam4.492
PMCID: PMC4618619

Genes

ALK
EGFR
KRAS

Variants

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