Article
In silico saturation mutagenesis of cancer genes
2020-06-04
Abstract excerpt
<h4>Summary</h4> Extensive bioinformatics analysis of datasets of tumor somatic mutations data have revealed the presence of some 500-600 cancer driver genes. The identification of all potential driver mutations affecting cancer genes is essential to implement precision cancer medicine and to understand the interplay of mutation probability and selection in tumor development. Here, we present an in silico saturat...
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Identifiers and source
- Literature Corpus work
- 907ae725-804e-54ae-a736-40b30b194d6d
- DOI
- 10.1101/2020.06.03.130211