Article

Modeling Functional Genetic Alteration in Cancer Reveals New Candidate Driver Genes

2018-01-05

Abstract excerpt

Compiling the catalogue of genes actively involved in tumorigenesis (known as cancer drivers) is an ongoing endeavor, with profound implications to the understanding of tumorigenesis and treatment of the disease. An abundance of computational methods have been developed to screening the genome for candidate driver genes based on genomic data of somatic mutations in tumors. Most methods rely on detecting genes disp...

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Literature Corpus work: aaafa2b9-4745-5568-a33f-0780de9d92a6
DOI: 10.1101/242354

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