Article

Intrinsic base substitution patterns in diverse species reveal links to cancer and metabolism

2019-09-08

Abstract excerpt

Analyses of large-scale sequencing data reveal that mutagenic processes create distinctive patterns of base substitutions, called mutational signatures. Here, we analyzed substitution patterns from seven model species and single nucleotide polymorphisms (SNPs) in 42 species, totalling >1.9 billion variants. We found that the base substitution patterns for many species most closely match mutational signature 5 in c...

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Literature Corpus work: 9054ce6f-66ce-5322-ae55-5847f4888b60
DOI: 10.1101/758540

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