Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases.

doi:10.1038/srep44547

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Article

Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases.

Scientific reports - 17 Mar 2017

Maschietto Mariana, Bastos Laura Caroline, Tahira Ana Carolina, Bastos Elen Pereira, Euclydes Veronica Luiza Vale, Brentani Alexandra, Fink Günther, de Baumont Angelica, Felipe-Silva Aloísio, Francisco Rossana Pulcineli Vieira, Gouveia Gisele, Grisi Sandra Josefina Ferraz Ellero, Escobar Ana Maria Ulhoa, Moreira-Filho Carlos Alberto, Polanczyk Guilherme Vanoni, Miguel Euripedes Constantino, Brentani Helena

Abstract excerpt

Sex differences in the prevalence of psychiatric disorders are well documented, with exposure to stress during gestation differentially impacting females and males. We explored sex-specific DNA methylation in the cord blood of 39 females and 32 males born at term and with appropriate weight at birth regarding their potential connection to psychiatric outcomes. Mothers were interviewed to gather information about...

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PMID: 28303968
DOI: 10.1038/srep44547
PMCID: PMC5355991

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