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Efflux pump mutations in <i>Pseudomonas aeruginosa</i> cause low-level clinical resistance and high-level tolerance to antibiotics in patients

2023-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Pseudomonas aeruginosa is one of the microorganisms with high-risk regarding antimicrobial resistance, since it has an overwhelming capacity to acquire antibiotic resistance, mainly by mutations during persistent lung infections. Mutations in mexZ , encoding the local negative regulator of genes encoding the MexXY efflux pump, are very frequently acquired at early stages of P. aeruginosa infec...

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Literature Corpus work
902e130f-cce1-50f0-968e-b5e0604c86a1
DOI
10.1101/2023.08.18.553894
Open publication

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Efflux pump mutations in <i>Pseudomonas aeruginosa</i> cause low-level clinical resistance and high-level tolerance to antibiotics in patientsDOI 10.1101/2023.08.18.553894
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